| Participants |
50 participants, aged between 11 and 65 years
Inclusion criteria
Cystic fibrosis with or without lung transplantion Allergic chronic rhinosinusitis or no allergic diagnosed by the clinical investigator on the basis of the following signs in variable combination: nasal congestion, headache, sneezing, itchy nose and eyes, runny nose, nosebleeds and nasal crusts, redness and eye discharge present more than 3 months per year. Treated on an outpatient basis No sea baths for the duration of the study Respect the procedures for conducting the study, in particular the washout period and follow‐up visits Capable of understanding and self‐completing the questionnaires; For juveniles, the holder (s) of parental authority have accepted the participation of the young person (by signing the informed consent after having taken note of the information note) Member or beneficiary of a social security program
Exclusion criteria
Significant obstruction of the nasal passages due to: a mucocele, polyposis causing nasal obstruction > 90%, or severe malformation of the septum causing a nasal obstruction > 90% in whom surgical treatment is recommended Signs of severity that may require hospitalization, such as: severe impairment of general health, dyspnoea with cyanosis, high fever (> 40 ° C) Corticosteroid therapy required during the study, with the exception of those who received pulmonary transplant and were treated with oral corticosteroids at no more than 0.2 mg / kg / day Known systemic immunodeficiency status with the exception of those receiving pulmonary transplantation and immunosuppressed Pregnant (urine test) or without effective contraception (birth control pill, contraceptive patch, contraceptive implant, vaginal ring, intrauterine device or intrauterine device, male condom). Nursing Contraindication to nasal irrigations as defined in the product leaflet
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