Table 3.
Relative difference in functional measures between the case- and control-group within each ICF-dimension
| ICF | Variables | Cases (n = 28) |
Controls (n = 31) | ES or Med d | ES or Med d 95% CI | Stats t, χ2, U, M |
P | E Abs ES or C’s d |
|---|---|---|---|---|---|---|---|---|
| Body Function | Pain last wk., Med (IQR) (R) | 3.5 (4.8) | 0.0 (1.0) | 3.0 | 3.0, 5.0 | 0.000 (U) | 2.0E-12§ | 3.3 |
| KOOS Pain, Med (IQR) | 58.8 (18.8) | 98.4 (3.6) | −38.9 | −52.8, −30.6 | 5.0 (U) | 1.8E-11§ | 3.2 | |
| KOOS Symptoms, Med (IQR) | 58.9 (33.9) | 98.4 (3.6) | −35.8 | −42.9, −28.6 | 4.0 (U) | 4.6E-11§ | 3.2 | |
| Pain-10StUpDw, Med (IQR) (R) | 2.0 (3.0) | 0.0 (3.0) | 2.0 | 1.0, 3.0 | 108 (U) | 1.7E-08§ | 1.7 | |
| Pain-30sCST, Med (IQR) | 2.0 (5.0) | 0.0 (0.1) | 2.0 | 1.0, 4.0 | 124 (U) | 2.4E-08§ | 1.6 | |
| Pain-6MWT, Med (IQR) (R) | 3.5 (6.8) | 0.0 (3.0) | 2.0 | 0.0, 5.0 | 130 (U) | 0.00061‡ | 1.5 | |
| Pain-TUG, Med (IQR) | 0.1 (2.7) | 0.0 (0.1) | 0.2 | 0.0, 1.0 | 217 (U) | 1.0E-5‡ | 0.9 | |
| Knee ext. strength inv. leg, M (SD) | 1.16 (0.48) | 1.46 (0.38) | −0.7 | −0.2, −1.2 | 1.592 (t) | 0.010* | 0.7 | |
| 30sTSLS inv. leg (s), Med (IQR) | 11.0 (25.4) | 29.8 (7.3) | −9.1 | −21.1, 0.0 | 292 (U) | 0.0291* | 0.6 | |
| 30sCST (n), M (SD) | 14.0 (4.2) | 16.3 (4.2) | −0.5 | − 1.1, 0.0 | −2.1 (t) | 0.0422 | 0.5 | |
| Knee ext. stren., uninv. leg, M (SD) | 1.45 (0.36) | 1.64 (0.46) | −0.5 | −1.0, 0.1 | − 1.74 (t) | 0.088 | 0.5 | |
| TSLS uninv leg (s), Med (IQR) | 15.9 (23.5) | 29.5 (16.0) | −5.4 | −14.1, 0.0 | 329 (U) | 0.1071 | 0.4 | |
| RPE-6MWT, M (SD) | 6.0 (1.8) | 5.5 (1.7) | 0.3 | −0.2, 0.8 | 1.1 (t) | 0.2577 | 0.3 | |
| RPE-10StUpDwT, M (SD) | 3.3 (1.7) | 3.1 (1.3) | 0.2 | −0.3, 0.7 | 0.6 (t) | 0.5368 | 0.2 | |
| RPE-30sCST, Med (IQR) | 3.0 (3.0) | 3.0 (2.0) | 0.0 | −1.0, 1.0 | 420 (U) | 0.8266 | 0.1 | |
| Activity | KOOS Sport/Rec, Med (IQR) | 30.0 (25.6) | 100 (5.0) | −65.0 | −75.0, −60.0 | 4.0 (U) | 2.3E-11§ | 3.2 |
| KOOS ADL, Med (IQR) (R) | 67.7 (39.6) | 100.0 (13.9) | −32.4 | −38.2, −14.7 | 28.5 (U) | 9.5E-11§ | 2.7 | |
| 10StUpDwT (s), M (SD) | 10.8 (3.1) | 7.8 (1.1) | 1.3 | 0.7, 1.9 | 5.0 (t) | 3.6E-05‡ | 1.3 | |
| Timed Up-and-Go (s), M (SD) | 6.6 (1.2) | 5.7 (0.9) | 0.9 | 0.3, 1.4 | 3.4 (t) | 0.0014† | 0.9 | |
| 6MWT (m), M (SD) | 642.5 (94.6) | 717.4 (75.4) | −0.9 | −1.4, −0.3 | −3.4 (t) | 0.0014† | 0.9 | |
| Participation | KOOS QoL, Med (IQR) (R) | 43.8 (25.0) | 100.0 (25.0) | −56.2 | −62.5, −43.8 | 1.0 (U) | 9.8E-12§ | 3.3 |
| Örebo PsySoc, M (SD) | 39.0 (12.7) | 12.8 (9.6) | 2.3 | 1.7, 3.0 | 9.0 (t) | 1.6E-12§ | 2.3 | |
| Vig.-int. act. (min/wk), Med (IQR) | 1.0 (15.3) | 29.0 (63.0) | −23.0 | −46.0, −10 | 167.5 (U) | 4.5E-05‡ | 1.2 | |
| EUROHIS-QoL, Med (IQR) | 33.0 (4.4) | 36.0 (6.0) | −3.0 | −5.0, −1.0 | 274.5 (U) | 0.015* | 0.7 | |
| Mod.-int. act. (min/wk), M (SD) | 286.0 (169.1) | 382.5 (134.5) | −0.6 | −1.2, −0.1 | −2.4 (t) | 0.018* | 0.6 | |
| Light-int. act. M (SD) | 1553.0 (444.9) | 1494.9 (468.6) | 0.1 | −0.4, 0.6 | 0.5 (t) | 0.63 | 0.1 | |
| Sed.-int. act. (min/wk); M (SD) | 8141.9 (663.1) | 8197.5 (662.9) | −0.1 | −0.6, 0.4 | −0.3 (t) | 0.74 | 0.1 |
Notes. Case = patients with knee osteoarthritis, control = individuals without knee complaints; ICF = = the International Classification of Function, Disability, and Health (of the WHO); ES = effect size by Cohen’s d or mean difference between groups divided by the variability of groups; Med d = median difference; CI = confidence interval; Stats = statistics; P = probability value; E = estimated; Abs = absolute value; ES = effect size or Cohen’s d; C’s d = Cohen’s d.; KOOS = Knee Injury and Osteoarthritis Outcome Scale; Med = median; IQR = interquartile range; R = range (given for the controls when the IQR was not obtainable); 10StUpDw = 10 step up-and-down stair climb test; 30sCST = number of Chair-to-Stand raises in 30 s test; 6MWT = test of distance walked in 6 minutes; TUG = Time up-and-go test or seconds taken to rise from a chair, walk 3 m, turn, walk back, and sit down; 30sTSLS inv. leg = 30 s timed single-leg standing on the involved leg; RPE = Rate of Perceived exertion on the Borg Category Rating Scale; Sports/Rec = sports and recreation scale; ADL = activity of daily life; QoL = Quality of Life; PsycSoc. = psychosocial questionnaire; Vig.-int. Act. = Vigorous-intensity physical activity of daily life; Mod. = moderate; Sed. = sedentary; * = significant result, † = highly significant result, ‡ = very highly significant result, § = extremely highly significant result