Table 4.
Univariate and multivariate Cox proportional Hazard modeling results of MACE
| Variables | Univariate model | Multivariate model | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | |
| Age | 1.018 | 1.000–1.037 | 0.049 | 1.005 | 0.985–1.026 | 0.618 |
| Male sex | 1.678 | 1.083–2.599 | 0.02 | 1.281 | 0.768–2.138 | 0.343 |
| Smoking | 1.113 | 0.754–1.642 | 0.59 | – | – | – |
| Drinking | 1.185 | 0.798–1.760 | 0.4 | – | – | – |
| Hypertension | 1.528 | 1.025–2.277 | 0.037 | 1.551 | 0.996–2.416 | 0.052 |
| Family history | 1.536 | 0.975–2.420 | 0.064 | – | – | – |
| Hypercholesterolemia | 1.244 | 0.842–1.838 | 0.273 | – | – | – |
| Diabetes | 1.919 | 1.295–2.843 | 0.001 | 1.911 | 1.241–2.941 | 0.003 |
| LVEF (%) | 0.989 | 0.967–1.011 | 0.32 | – | – | – |
| HR | 1.024 | 1.006–1.042 | 0.01 | 1.021 | 1.001–1.041 | 0.042 |
| WBC | 1.076 | 1.000–1.156 | 0.049 | 1.010 | 0.930–1.097 | 0.812 |
| HB | 0.978 | 0.965–0.991 | 0.001 | 0.980 | 0.965–0.995 | 0.008 |
| RDW | 1.134 | 0.941–1.366 | 0.187 | – | – | – |
| PLT | 1 | 0.997–1.002 | 0.791 | – | – | – |
| BUN | 1.077 | 0.966–1.200 | 0.18 | – | – | – |
| FBG | 1.087 | 1.027–1.150 | 0.004 | 0.998 | 0.934–1.067 | 0.958 |
| TG | 0.979 | 0.837–1.146 | 0.795 | – | – | – |
| TC | 0.993 | 0.842–1.172 | 0.937 | – | – | – |
| LDL-C | 1.428 | 1.230–1.657 | < 0.001 | 1.411 | 1.178–1.690 | < 0.001 |
| DBIL | 1.062 | 0.980–1.150 | 0.143 | – | – | – |
| IBIL | 0.972 | 0.932–1.012 | 0.171 | – | – | – |
| Gensini score | 1.006 | 1.001–1.011 | 0.022 | 1.006 | 1.001–1.011 | 0.029 |
| MHR | 3.414 | 2.148–5.427 | < 0.001 | 2.390 | 1.379–4.143 | 0.002 |
| MHR quartiles | ||||||
| Q1 | Ref | Ref | – | Ref | Ref | – |
| Q2 | 1.576 | 0.833–2.982 | 0.162 | 1.652 | 0.844–3.233 | 0.143 |
| Q3 | 2.654 | 1.414–4.981 | 0.002 | 2.831 | 1.433–5.596 | 0.003 |
| Q4 | 4.357 | 2.344–8.099 | < 0.001 | 3.258 | 1.604–6.619 | 0.001 |