Table 3.
Multivariate analysis of risk factors associated with OS and PFS
| Variables | OS | PFS | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| B symptoms (yes vs. no) | 1.52 (1.08–2.16) | 0.011 | 1.31 (1.04–1.67) | 0.056 |
| Lugano stage (I–II2 vs. III–IV) | 2.64 (1.45–5.09) | 0.162 | 1.70 (0.59–4.88) | 0.327 |
| LDH (elevated vs. normal) | 0.55 (0.16–2.41) | 0.098 | 0.36 (0.11–1.20) | 0.172 |
| Local tumor invasiveness (yes vs. no) | 0.60 (0.32–1.89) | 0.048 | 0.52 (0.25–1.11) | 0.074 |
| Treatment (chemotherapy alone or radiotherapy alone vs. both) | 1.09 (0.10–3.21) | 0.041 | 0.71 (0.22–2.30) | 0.109 |
| Absolute lymphocyte count (≤ 1.5 × 109/L vs. > 1.5 × 109/L) | 2.05 (0.34–5.80) | 0.200 | 1.57 (1.06–2.33) | 0.428 |
| LMR (≤ 2.7 vs. > 2.7) | 1.95 (0.75–4.09) | 0.009 | 1.41 (0.34–4.80) | 0.025 |