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. 2019 Oct 21;20:225. doi: 10.1186/s12931-019-1184-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Reduced miR-335-5p expression and increased ROCK1 expression are associated with lymph node metastasis in NSCLC tissues. a, d Reduced miR-335-5p expression and increased ROCK1 expression were associated with lymph node metastasis in NSCLC tissues when compared to NSCLC tissues without metastasis. b, e Kaplan-Meier analysis showed that patients with higher miR-195-5p expression and lower ROCK1 expression were associated with favorable overall survival. c, f MiR-335-5p expression was negatively related with MMP2 and Vimentin expression in 447 patient samples. And the expression of ROCK1 is positively associated with MMP2 and Vimentin expression in 515 patient samples. g IHC analysis of ROCK1 expression in lymph-node matastasis and non-lymph node metastasis group. *P < 0.05