Table 2.
Surgical and perioperative treatments
| Category of perioperative treatments | PCC (+) n = 12 |
PCC (−) n = 113 |
P |
|---|---|---|---|
| Types of surgical correction | |||
| Aortic sinus reconstruction | 3(25.0%) | 17(15.0%) | 0.406 |
| Bentall | 1(8.3%) | 11(9.7%) | 1.000 |
| Wheat | 0 (0.0%) | 2(1.8%) | 1.000 |
| Hemiarch replacement | 12(100%) | 106(93.8%) | 1.000 |
| Ascending aorta replacement | 12(100%) | 105(92.9%) | 1.000 |
| CABG | 0(0.0%) | 1(0.9%) | 1.000 |
| Intraoperative conditions | |||
| Surgery (min) | 303.6 ± 43.0 | 282.4 ± 55.9 | 0.113 |
| CPB (min) | 165.4 ± 42.5 | 134.8 ± 21.5 | 0.010 |
| Aortic cross-clamping (min) | 50.8 ± 7.6 | 46.8 ± 7.9 | 0.064 |
| MHCA+ SCP (min) | 20.3 ± 2.1 | 15.5 ± 2.7 | 0.000 |
| Blood loss (ml) | 475.0 ± 256.3 | 374.8 ± 166.5 | 0.059 |
| Avg rcSO2 baseline (%)a | 48.2 ± 3.3 | 66.7 ± 11.7 | 0.000 |
| Avg rcSO2 (%)(L) | 56.5 ± 8.2 | 58.7 ± 9.9 | 0.505 |
| Avg rcSO2 (%)(R) | 57.3 ± 7.1 | 59.6 ± 11.7 | 0.560 |
| rcSO2 minimum (%) | 50.6 ± 7.8 | 54.7 ± 7.3 | 0.077 |
| Total time of rcSO2 < 70% baseline and > 15 s (n) | 4.6 ± 1.8 | 3.6 ± 2.4 | 0.174 |
| Total time of rcSO2 < 50% and > 15 s (n) | 1.7 ± 1.0 | 1.3 ± 1.6 | 0.099 |
| AUC of rcSO2 < 70% (%min)(L) | 150.3 ± 63.0 | 121.2 ± 75.5 | 0.227 |
| AUC of rcSO2 < 70% (%min)(R) | 120.3 ± 117.0 | 98.5 ± 63.5 | 0.917 |
| AUC of rcSO2 < 50% (%min)(L) | 86.6 ± 62.7 | 61.4 ± 64.1 | 0.145 |
| AUC of rcSO2 < 50% (%min)(R) | 52.7 ± 32.3 | 45.9 ± 49.7 | 0.303 |
| Avg BIS index | 36.8 ± 10.3 | 39.8 ± 9.3 | 0.320 |
| Perioperative allogeneic transfusion | |||
| RBC (u) | 2.7 ± 1.8 | 3.1 ± 2.8 | 0.727 |
| PLT (u) | 0.8 ± 1.2 | 1.2 ± 1.9 | 0.201 |
| FFP (ml) | 366.7 ± 602.0 | 313.7 ± 345.8 | 0.666 |
| CP (U) | 1.0 ± 2.3 | 1.5 ± 2.8 | 0.528 |
The results demonstrated that there were significant differences between the two groups in terms of the duration of CPB and MHCA+SCP. The monitoring of rcSO2 indicated that there were no significant differences between the two groups in terms of intraoperative rcSO2 except for the average value of bilateral rcSO2 at baseline
PCC Postoperative cerebral complications, CABG Coronary artery bypass grafting, CPB Cardiopulmonary bypass, MHCA Moderate hypothermic circulatory arrest, SCP Selective cerebral perfusion, rcSO2 regional cerebral oxygen saturation, AUC Area under the curve, RBC Red blood cell, PLT Platelet, FFP Fresh frozen plasma, CP Cryoprecipitation
athe baseline value of rcSO2 from the bilateral brain before anesthesia induction