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. 2019 Oct 21;19:228. doi: 10.1186/s12872-019-1210-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Atrial fibrillatory rate. Left: Example of spatiotemporal QRST cancellation: From the surface ECG (top trace), the software identifies the QRS complexes. After QRST cancellation, only the atrial signal remains (bottom trace). Right: The course of AFR during the study. AFR increases significantly (p < 0.01) from day 1 to day 55 consistent with atrial remodeling. n = 6 except day 3 (n = 2). Data are presented as mean ± SD. AFR = atrial fibrillatory rate, fpm = fibrillations per minutes. Asterisks indicate statistical significance (p < 0.01)