Fig. 5.

Overexpression of miR-129-5p or down-regulation of ZIC2 inhibits PCa cell proliferation. DU-145 cells were treated with miR-129-5p mimic, miR-129-5p inhibitor or/and si-ZIC2. a The OD values at the 24th, 48th, and 72nd h in DU-145 cells. b Cell survival rate after 48 h of transfection. The data are summarized as mean ± standard deviation; the repeated measurement analysis of variance was conducted to compare cell proliferation at different time points. The experiment was performed three times. *p < 0.05 vs. the blank and NC groups