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. 2019 Oct 21;10:308. doi: 10.1186/s13287-019-1406-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Representative images of quantitative MRI mappings of three patients from high (60 years, F), middle (68 years, M), and low (65 years, M) dose groups. For the same patient, the change (red arrow) of the T1rho (a) image was more obvious than that of the T2 (b), T2star (c), R2 star (d), and ADC (e) images. Changes of T1rho values between two examination time points in the patient from the high-dose group were more pronounced than those from the other two groups, whereas this phenomenon was not found in other MRI images