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. 2019 Oct 16;10:1224. doi: 10.3389/fphar.2019.01224

Figure 5.

Figure 5

The antioxidative and antiapoptotic functions of fibroblast growth factor 10 (FGF10) are mediated by the activation of the PI3K/Akt pathway in vivo. (A–D) Representative western blots and the quantification of p-Akt, Akt, Nrf2, and HO-1 expression in each group. (E–G) Western blotting and the quantification of Bcl-2 and Bax expression 28 days after injury. The data are presented as the mean ± SEM, n = 3. Sham group vs peripheral nerve injury (PNI) group: *P < 0.05, ***P < 0.001. FGF10 group vs PNI group: ***P < 0.001. FGF10 group vs FGF10+LY294002 group: *P < 0.05, **P < 0.01.