Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 16;7:243. doi: 10.3389/fcell.2019.00243

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Lu, Lv, Kong, Chen, Duan, Chen, Sun, Fang and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

MRTF-A regulates Abl1 expression in activated hepatic stellate cells in vitro. (A,B) Primary HSCs isolated from WT and MRTF-A KO mice were spontaneously activated in culture for 7 days. Gene expression levels were examined by qPCR and Western. (C,D) LX-2 cells were transfected with small interfering RNA targeting MRTF-A or scrambled siRNA (SCR) followed by treatment with PDGF-BB. Gene expression levels were examined by qPCR and Western. (E,F) LX-2 cells were treated with PDGF-BB in the presence or absence of CCG-1423 (1–10 μM). Gene expression levels were examined by qPCR and Western. All experiments were repeated three times and one representative experiment is shown. Error bars represent SD (^∗p < 0.05, one-way ANOVA with post hoc Scheffe test).