Table 5.
Cox's proportional hazards regression model analysis of factors affecting OS
| Parameters | Cox's regression | |||
|---|---|---|---|---|
| P value | HR | 95% CI | ||
| Lower | Higher | |||
| Univariate Cox's regression | ||||
| Age (≥60 y vs <60 y) | 0.187 | 0.498 | 0.177 | 1.403 |
| Gender (male vs female) | 0.220 | 2.542 | 0.573 | 11.272 |
| Relapsed vs de novo | 0.513 | 1.438 | 0.484 | 4.271 |
| Number of nodules (≥2 vs 1) | 0.057 | 7.164 | 0.942 | 54.510 |
| Largest nodule size (≥5 cm vs <5 cm) | 0.045 | 3.242 | 1.029 | 10.215 |
| Child‐Pugh stage (B vs A) | 0.030 | 3.623 | 1.130 | 11.618 |
| BCLC stage (B/C vs A) | 0.056 | 4.279 | 0.964 | 18.997 |
| Cycles of DEB‐TACE (≥2 vs 1) | 0.036 | 0.273 | 0.081 | 0.918 |
| AFP (≥98.8 μg/L vs <98.8 μg/L) | 0.266 | 1.862 | 0.622 | 5.569 |
| Multivariate Cox's regression | ||||
| Child‐Pugh stage (B vs A) | 0.011 | 4.803 | 1.426 | 16.180 |
| BCLC stage (B/C vs A) | 0.044 | 4.752 | 1.044 | 21.621 |
Data were presented as P value, HR (hazards ratio), and 95% CI (confidence interval). Factors affecting OS were determined by univariate and multivariate Cox's proportional hazards regression model analyses, and the multivariate Cox's proportional hazards regression model analysis was performed using Forward Stepwise (Conditional LR) method. P value <0.05 was considered significant.
Abbreviations: AFP, alpha‐fetoprotein; BCLC, Barcelona Clinic Liver Cancer; DEB‐TACE, drug‐eluting bead transarterial chemoembolization; OS, overall survival.