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. 2019 Oct 18;10:359–371. doi: 10.2147/JBM.S189922

Table 1.

Unique Risk Factors For Thrombotic Complications

Risk Factor Comments
Gender Differences Women:
  • ↓ age at diagnosis

  • ↑ rates of AVT

Driver Mutational Status
  • JAK2 V617F allele burden

Inflammatory Markers Role of Pentraxins:
  • ↑ hs-CRP

  • ↓ PTX3

Microparticles MPs associated with:
  • ↓ thrombin inhibition

  • ↑ CD41

  • ↑ splenomegaly

Neutrophil Extracellular Trap Formations (NETs) Result in NETosis and apoptosis

Abbreviation: AVT, abdominal vein thrombosis.