Table 2.
Adjusted odds ratio for metronidazole treatment failure stratified by the continuous use of antibiotics among patients with CDI
| Use of concomitant antibiotics | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall | Without | With | |||||||
| Groups | ORa | 95% CI | P value | ORa | 95% CI | P value | ORa | 95% CI | P value |
| Non-CKD | Reference | Reference | Reference | ||||||
| Non-dialysis CKD | 0.69 | 0.27–1.77 | 0.441 | 0.42 | 0.05–3.50 | 0.425 | 0.85 | 0.27–2.71 | 0.787 |
| Dialysis | 2.09 | 1.03–4.21 | 0.040 | 2.87 | 1.03–8.02 | 0.044 | 1.38 | 0.49–3.91 | 0.541 |
CKD, chronic kidney disease; CI, confidence interval; OR, odds ratio.
a
OR was adjusted for age, sex, serum albumin, fever, risk-stratified concomitant antibiotic use, use of glycopeptide, number of antibiotics used (⩾2 or <2) and leukocytosis (WBC > 15 000/μl).