Table 3.
Univariate and multivariate Cox analysis of survival in patients with primary renal lymphoma (PRL) by different clinical variables.
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR | p | HR | p | |
| Age | ||||
| ≤60 | ||||
| 61–80 | 1.86 (1.46–2.38) | <0.001 | 1.90 (1.47–2.44) | <0.001 |
| >80 | 2.98 (2.13–4.18) | <0.001 | 3.34 (2.34–4.77) | <0.001 |
| Sex | ||||
| Female | ||||
| Male | 1.33 (1.06–1.65) | 0.012 | 1.38 (1.10–1.73) | 0.005 |
| Race | ||||
| White | ||||
| Other | 0.92 (0.66–1.27) | 0.598 | 1.19 (0.85–1.67) | 0.314 |
| Unknown | 1.05 (0.14–7.51) | 0.958 | 0.84 (0.12–6.13) | 0.864 |
| Year | ||||
| 1980–1999 | 1.33 (1.06–1.68) | 0.014 | 1.40 (1.10–1.80) | 0.007 |
| 2000–2013 | ||||
| Laterality | ||||
| Right | ||||
| Left | 0.89 (0.71–1.10) | 0.282 | 0.89 (0.71–1.11) | 0.311 |
| Bilateral | 0.79 (0.53–1.18) | 0.250 | 0.78 (0.51–1.19) | 0.247 |
| Unknown | 0.66 (0.35–1.26) | 0.206 | 0.58 (0.29–1.13) | 0.111 |
| Stage | ||||
| Stage I & II | ||||
| Stage III & IV | 1.40 (1.12–1.74) | <0.001 | 1.39 (1.11–1.75) | 0.004 |
| Unknown | 1.95 (1.35–2.81) | <0.001 | 1.67 (1.14–2.47) | 0.009 |
| Surgery | ||||
| Surgery | ||||
| Non-surgery | 1.41 (1.13–1.76) | 0.003 | 1.50 (1.18–1.91) | 0.001 |
| Unknown | 1.49 (0.83–2.65) | 0.181 | 1.46 (0.79–2.70) | 0.224 |
| Histology | ||||
| Marginal zone lymphoma | ||||
| Follicular lymphoma | 2.01 (1.06–3.79) | 0.032 | 1.97 (1.04–3.73) | 0.039 |
| Small lymphatic lymphoma | 2.03 (0.93–4.47) | 0.076 | 2.21 (1.00–4.89) | 0.051 |
| Burkitt’s lymphoma | 1.18 (0.49–2.86) | 0.708 | 1.51 (0.60–3.77) | 0.381 |
| DLBCL | 2.24 (1.28–3.94) | 0.005 | 2.48 (1.40–4.38) | 0.002 |
| T/NK cell lymphoma | 3.03 (0.99–9.29) | 0.053 | 4.37 (1.40–13.57) | 0.011 |
| Other | 2.18 (1.21–3.93) | 0.010 | 2.04 (1.11–3.73) | 0.021 |
Note: HR: Hazard ratios; CI: confidence interval; DLBCL: diffuse large B-cell lymphoma; *Included lymphoma, NOS (not otherwise specified); non-Hodgkin lymphoma, NOS and Hodgkin lymphoma.