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. 2019 Oct 22;9:15132. doi: 10.1038/s41598-019-51219-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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AUROC over the 48 hours directly preceding septic shock onset. Area under the ROC curve for LiSep LSTM (blue) when considering only predictions made within a number of hours before septic shock onset as indicated by the x-axis. Error bars show 95% CI and were generated by bootstrapping the evaluation results for the six trained model instances.