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. 2019 Oct 22;9:15110. doi: 10.1038/s41598-019-51756-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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RGC Response Delays Vary with Spectral Features of Light Stimuli. (a) Raster diagrams show representative ON-(top) and OFF-(bottom) RGC responses to photopic light stimuli of various spectral lengths (wavelengths are shown by the number to the left; six trials for each stimulus). Clearly, response delays were prone to stimulus wavelength changes. (b) Histogram displays variations of response delays (y axis) of individual RGCs (color coded) as a function of stimulus wavelength (x axis). ON-RGCs (top graph) seemed to be more sensitive to stimulus wavelength changes than those of OFF-RGC (bottom graph) counterparts. (c) Bar graph showing maximum response delay differences for both ON- and OFF-RGC responses. ON-cells showed significantly larger variation in the response delays than the examined OFF-RGC population (p = 0.0004; Mann-Whitney test).