Table 3.
ORs and HRs With 95% CIs for Mortality Associated With NMAPR in Patients With Different SOFA Scores
| Regression Models | Mortality | |||
|---|---|---|---|---|
| ICU, OR (95% CI) | Hospital, OR (95% CI) | 28 d, HR (95% CI) | 1 y, HR (95% CI) | |
| SOFA <8 (n=2522) | ||||
| Univariate | 1.36 (1.00–1.86) | 1.38 (1.05–1.82) | 1.32 (1.03–1.68) | 1.22 (1.01–1.48) |
| Multivariate | ||||
| Model 1 | 1.44 (1.05–1.98) | 1.47 (1.11–1.93) | 1.39 (1.09–1.78) | 1.30 (1.07–1.57) |
| Model 2 | 1.43 (1.04–1.97) | 1.45 (1.10–1.92) | 1.39 (1.09–1.78) | 1.29 (1.07–1.57) |
| Model 3 | 1.41 (1.01–1.96) | 1.44 (1.08–1.93) | 1.37 (1.08–1.75) | 1.29 (1.07–1.56) |
| Model 4 | 1.43 (1.01–2.02) | 1.44 (1.06–1.95) | 1.34 (1.05–1.71) | 1.24 (1.02–1.50) |
| SOFA ≥8 (n=2663) | ||||
| Univariate | 1.60 (1.28–1.99) | 1.57 (1.28–1.93) | 1.45 (1.20–1.75) | 1.42 (1.21–1.67) |
| Multivariate | ||||
| Model 1 | 1.60 (1.28–1.99) | 1.57 (1.27–1.93) | 1.45 (1.20–1.75) | 1.43 (1.22–1.68) |
| Model 2 | 1.60 (1.29–2.00) | 1.57 (1.27–1.94) | 1.45 (1.20–1.75) | 1.43 (1.22–1.68) |
| Model 3 | 1.48 (1.17–1.87) | 1.45 (1.16–1.82) | 1.31 (1.09–1.58) | 1.32 (1.12–1.55) |
| Model 4 | 1.39 (1.08–1.79) | 1.37 (1.07–1.75) | 1.25 (1.04–1.51) | 1.27 (1.08–1.49) |
Model 1 was adjusted for age, sex, and ethnicity. Model 2 was adjusted for model 1 plus an average of mean arterial pressure. Model 3 was adjusted for model 2 plus ventilation. Model 4 was adjusted for model 3 plus primary diagnoses: heart failure, diabetes mellitus, hypertension, hypotension, coronary heart disease, cerebral hemorrhage, shock, respiration failure, renal failure, self‐poisoning, infection, coma, and delirium. HR indicates hazard ratio; ICU, intensive care unit; NMAPR, nocturnal mean arterial pressure rising; OR, odds ratio; SOFA, Sequential Organ Failure Assessment.