Table 3.
Bacterial Taxa Found to Be Differentially Present in Blood According to the Onset of MI After Adjustment on Cardiovascular Risk Factors (Chi‐Square/Fisher Exact Test for Presence/Absence)
| Controls, N (%) | Cases, N (%) | P Value | Adjusted P Value* | Adjusted Odds Ratio (95% CI) | |
|---|---|---|---|---|---|
| Order level | |||||
| Caulobacterales | 54 (54.5) | 30 (30.9) | 0.001 | <0.001 | 0.24 (0.11–0.54) |
| Neisseriales | 27 (27.3) | 14 (14.4) | 0.027 | 0.019 | 0.32 (0.12–0.83) |
| Family level | |||||
| Caulobacteraceae | 53 (53.5) | 30 (30.9) | 0.001 | 0.001 | 0.27 (0.12–0.59) |
| Clostridiales‐incertae‐sedis‐XI | 29 (29.3) | 13 (13.4) | 0.007 | 0.026 | 0.34 (0.13–0.88) |
| Microbacteriaceae | 82 (82.8) | 56 (57.7) | <0.001 | 0.001 | 0.27 (0.12–0.59) |
| Neisseriaceae | 27 (27.3) | 14 (14.4) | 0.027 | 0.020 | 0.32 (0.12–0.84) |
| Genus level | |||||
| Brevundimonas | 26 (26.3) | 14 (14.4) | 0.040 | 0.002 | 0.15 (0.04–0.49) |
| Chryseobacterium | 46 (46.5) | 29 (29.9) | 0.017 | 0.026 | 0.42 (0.19–0.90) |
| Gordonia | 50 (50.5) | 24 (24.7) | <0.001 | 0.012 | 0.39 (0.18–0.81) |
| Hymenobacter | 10 (10.1) | 23 (23.7) | 0.011 | 0.036 | 2.79 (1.07–7.30) |
| Microbacterium | 68 (68.7) | 45 (46.4) | 0.002 | 0.005 | 0.35 (0.17–0.73) |
MI indicates myocardial infarction.
*
Adjustment for age, sex, treated hypertension, treated dyslipidemia, treated diabetes mellitus, and current smoking.