Table 1.
Baseline clinical characteristics and lipid profiles
| Total (n = 654) | Non-statin group (n = 246) | Statin-taking group (n = 408) | P between groups | |
|---|---|---|---|---|
| CCTA inter-scan interval, years | 3.9 ± 1.5 | 3.8 ± 1.4 | 3.9 ± 1.5 | 0.557 |
| Age, years | 61.0 ± 9.9 | 60.2 ± 10.4 | 61.4 ± 9.4 | 0.150 |
| Male gender, n (%) | 365 (55.8) | 147 (59.8) | 218 (53.4) | 0.115 |
| Body mass index, kg/m2 | 24.8 ± 3.1 | 24.8 ± 3.2 | 24.8 ± 3.1 | 0.919 |
| Hypertension, n (%) | 371 (56.9) | 124 (50.4) | 247 (60.8) | 0.009 |
| Diabetes mellitus, n (%) | 157 (24.0) | 47 (19.1) | 110 (27.0) | 0.022 |
| Hyperlipidaemia, n (%) | 157 (24.0) | 24 (9.8) | 133 (32.6) | <0.001 |
| Family history of CAD, n (%) | 162 (24.8) | 62 (25.2) | 100 (24.5) | 0.842 |
| Smoking history, n (%) | 238 (36.4) | 94 (38.2) | 144 (35.3) | 0.467 |
| Typical chest pain, n (%) | 23 (3.5) | 5 (2.0) | 18 (4.4) | 0.128 |
| Atypical chest pain, n (%) | 527 (80.6) | 192 (78.0) | 335 (82.1) | 0.221 |
| Asymptomatic, n (%) | 8 (1.2) | 3 (1.2) | 5 (1.2) | >0.999 |
| Lipid profile at baseline (mg/dL) | ||||
| Total cholesterol | 183.9 ± 37.3 | 177.7 ± 30.2 | 187.7 ± 40.6 | <0.001 |
| Low-density lipoprotein | 114.7 ± 34.5 | 111.2 ± 27.5 | 116.8 ± 38.0 | 0.033 |
| High-density lipoprotein | 48.4 ± 13.4 | 48.6 ± 14.4 | 48.2 ± 12.7 | 0.716 |
| Triglycerides | 143.7 ± 82.2 | 136.3 ± 90.2 | 148.1 ± 76.8 | 0.093 |
| Lipid profile at follow-up (mg/dL) | ||||
| Total cholesterol | 168.3 ± 35.8 | 178.2 ± 30.3 | 162.3 ± 37.6 | <0.001 |
| Low-density lipoprotein | 94.5 ± 30.2 | 104.0 ± 25.7 | 88.8 ± 31.3 | <0.001 |
| High-density lipoprotein | 48.0 ± 11.7 | 47.9 ± 11.2 | 48.1 ± 12.1 | 0.799 |
| Triglycerides | 128.8 ± 73.1 | 133.2 ± 80.6 | 126.2 ± 68.2 | 0.246 |
CAD, coronary artery disease; CCTA, coronary computed tomography angiography; HDL, high-density lipoprotein; LDL, low-density lipoprotein.