. 2019 Mar 5;20(11):1250–1258. doi: 10.1093/ehjci/jez033

Table 2.

Diagnostic accuracy of best conventional and radiomic feature to identify invasive and radionuclide imaging markers of plaque vulnerability

Outcomes	Best conventional and radiomic parameter	AUC	P-value
IVUS-attenuated plaque	Conventional: non-calcified plaque volume	0.59 (0.57–0.62)	P < 0.001
IVUS-attenuated plaque	Radiomics: fractal box counting dimension of high attenuation voxels^a	0.72 (0.65–0.78)	P < 0.001
OCT-TCFA	Conventional: presence of low attenuation	0.66 (0.58–0.73)	P < 0.001
OCT-TCFA	Radiomics: fractal box counting dimension of high attenuation voxels^b	0.80 (0.72–0.88)	P < 0.001
NaF¹⁸-PET positivity	Conventional: presence of two high-risk features	0.65 (0.64–0.66)	P < 0.001
NaF¹⁸-PET positivity	Radiomics: surface of high attenuation voxels^b	0.87 (0.82–0.91)	P < 0.001

Values in parenthesis indicate confidence intervals.

AUC, area under the curve; IVUS, intravascular ultrasound; NaF¹⁸-PET, NaF¹⁸-positron emission tomography; OCT-TCFA, optical coherence tomography identified thin-cap fibroatheroma.

Component 30 when discretizing to 32 equally sized bins.

Component 8 when discretizing to eight equally sized bins.