Table 3.
Univariate and multivariate logistic regression analyses for association between CAD and various parameters
| Variables | Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value | |
| Age (per year) | 1.02 | 1.00–1.04 | 0.02 | 1.03 | 1.01–1.05 | 0.002 |
| Sex (male) | 2.24 | 1.48–3.38 | 0.0001 | 2.13 | 1.38–3.30 | 0.001 |
| Smoking | 1.63 | 1.10–2.43 | 0.02 | 1.59 | 1.05–2.43 | 0.03 |
| Hypertension | 1.40 | 0.93–2.09 | 0.10 | |||
| Hyperlipidaemia | 1.80 | 1.23–2.65 | 0.003 | 1.59 | 1.05–2.42 | 0.03 |
| Diabetes mellitus | 1.63 | 1.03–2.58 | 0.04 | 1.4 | 0.85–2.29 | 0.19 |
| BMI (kg/m2) | 0.98 | 0.95–1.02 | 0.05 | |||
| eGFR (mL/min*1.73 m2) | 0.99 | 0.98–1.00 | 0.12 | |||
| CIMT (per IQR) | 1.90 | 1.42–2.55 | <0.0001 | 1.59 | 1.17–2.16 | 0.003 |
| MPH (per IQR) | 2.32 | 1.72–3.14 | <0.0001 | 1.9 | 1.38–2.63 | <0.0001 |
| TPA (per IQR) | 1.92 | 1.47–2.51 | <0.0001 | 1.56 | 1.17–2.08 | 0.003 |
| aIPN (per score 0.25) | 2.41 | 2.08–2.79 | <0.0001 | 2.43 | 2.09–2.83 | <0.0001 |
aIPN, average intraplaque neovascularization; BMI, body mass index; CI, confidence interval; CIMT, carotid intima-media thickness; eGFR, estimated glomerular filtration rate; IQR, interquartile range; MPH, maximum plaque height; TPA, total plaque area.