Table 1.

The concentration of MK-801 in blood plasma and brain tissue 15, 30, 60, and 120 min after a single i.p. or s.c. administration of MK-801 at a dose of 0.1 mg/kg. Corresponds to Fig. 4A and B.

Group	Brain tissue, ng/g					Blood plasma, ng/ml
	Time (min)
	15	30	60	120	240	15	30	60	120	240
s.c.	96.50	71.86	34.70	14.09	3.94	4.54	4.55	2.29	0.84	0.19
	93.24	76.26	33.41	15.08	6.30	5.87	3.29	1.83	0.95	0.31
	73.02	73.10	40.87	13.32	5.52	4.47	3.75	2.52	0.66	0.18
	106.64	80.21	42.64	16.99	6.61
	98.41	71.87	38.85	21.92	7.97
	74.56	77.62	39.68	17.24	6.34
Mean	90.39	75.15	38.36	16.44	6.11	4.96	3.87	2.21	0.82	0.22
SEM	5.56	1.40	1.47	1.27	0.54	0.46	0.37	0.20	0.09	0.04
i.p.	41.18	44.10	17.20	11.95	6.20	2.10	2.69	0.98	0.79	0.24
	20.50	41.89	23.79	8.52	6.02	1.95	2.36	1.60	0.46	0.19
	37.49	47.57	24.91	7.98	6.97	3.06	2.90	1.45	0.59	0.30
	44.04	47.46	20.88	14.51	6.20
	30.18	46.87	24.01	12.46	7.45
	33.43	49.61	26.51	11.91	6.65
Mean	37.47	46.25	22.88	11.22	6.58	2.37	2.65	1.34	0.61	0.24
SEM	3.47	1.13	1.36	1.02	0.22	0.35	0.16	0.19	0.10	0.03
p	*	*	*	*	ns	*	*	*	ns	ns

The bold indicates the most important data of the table, as it shows the mean. ns – non-significant; s.c. — subcutaneous; i.p. — intraperitoneal.