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. 2019 Oct 22;322(16):1570–1579. doi: 10.1001/jama.2019.14969

Figure 2. Cumulative Incidence of Recurrent CIN Grade 2 or Higher and HSIL or More Severe Disease by Treatment Group.

Figure 2.

CIN indicates cervical intraepithelial neoplasia; HR, hazard ratio; HSIL, high-grade squamous intraepithelial lesion; LEEP, loop electrosurgical excision procedure. Median observation time for CIN grade 2 or higher: cryotherapy, 720 (interquartile range [IQR], 363-731) days; LEEP, 720 (IQR, 540-728) days. Median observation time for HSIL or more severe disease: cryotherapy, 720 (IQR, 214-729) days; LEEP, 720 (IQR, 361-728) days. Hazard ratios are adjusted for baseline histology, antiretroviral therapy use, and CD4 cell count as a time-varying coefficient.