Fig. 3.

YWHAZ was a direct target of miR-802 in epithelial ovarian cancer cells. a Bioinformatics analysis revealed predicted binding sites between miR-802 and YWHAZ. b Relative luciferase activity in cells co-transfected with miR-802 mimic or NC and pLUC-YWHAZ 3′-UTR wild type (WT) or pLUC-YWHAZ 3′-UTR mutant (MT) active. c The levels of YWHAZ in SKOV3 and OVCAR3 cells. d Expression levels of YWHAZ in epithelial ovarian cancer tissues and adjacent normal tissues. e Spearman correlation analysis of the correlation between miR-802 expression and YWHAZ mRNA expression.** P < 0.01