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. 2019 Oct 23;26:85. doi: 10.1186/s12929-019-0583-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Innate immune responses at 16 h post induction by the nanoparticle IT-101. (a)-(c) Changes in the proportions of cells in the myeloid cell lineage, including iDCs, neutrophils and macrophages, in peripheral blood, spleen and groin lymph nodes. (d)-(f) Changes in the proportions of cells in the lymphoid cell lineage, including Tc, Th, B and NK cells, in peripheral blood, spleen and groin lymph nodes. Number of mice per group: 3–6 mice. The results are presented as the mean ± SD. *p < 0.05; **p < 0.005; ***p < 0.0001