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. 2019 Oct 23;26:85. doi: 10.1186/s12929-019-0583-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — IT-101 attenuated the brain tumor growth at early stage of tumorigenesis. (a) (b) 2-month-old F1B transgenic mice were treated with IT-101 and PBS respectively by intravenous injection, one dose with booster doses. After two months ago, the tumor size was measured using histopathological data. (c) (d) 4-month-old F1B transgenic mice were treated with IT-101 and PBS respectively by Intraperitoneal injection, one dose with booster doses. After two months ago, the tumor size was measured using histopathological data. Mouse number per group, 3–5 mice. The results are presented as the mean ± SD. *p < 0.05; **p < 0.005