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. 2019 Oct 23;20:756. doi: 10.1186/s12864-019-6082-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Network clustering of P. ovis stage-specific gene expression profiles. A Pearson correlation matrix was generated comparing the gene expression data derived from all of the P. ovis life-cycle stages. A network graph was constructed using a Pearson correlation cut off value of 0.9. Each node (coloured circle) represents a single P. ovis gene. The network graph was clustered using an MCL inflation value of 2.2 with each cluster of genes being represented by a different colour. Clusters of genes exhibiting expression profiles specific to either single- or multiple-developmental stages of P. ovis are labelled as follows: Larvae (L), Protonymph (P), Tritonymph (T), Adult Female (AF) and Adult Male (AM)