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In vitro BMDC stimulation with, and uptake of, polyanhydride particles. (A) CD80/CD86 expression on the cell surface (flow cytometry) of BMDCs and (B) IL-10 and IL-12p70 concentrations in the cell-culture supernatants (ELISA) after a 24-hour incubation with empty polyanhydride particles. (C) uptake study by BMDCs of C6-loaded polyanhydride particles at two time points: 1 and 4 hours.
