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. 2019 Oct 3;20:497–511. doi: 10.1016/j.isci.2019.10.006

Figure 3.

Figure 3

VE-PTP Reduces Ang2-Induced Activation of Tie2, but Not Ang1

(A) VE-PTP is more effective in regulating Ang2-activated Tie2 compared to Ang1-activated Tie2.

(B) Simulation of concentration-dependent activation of Tie2 with VE-PTP by Ang1 and concentration-dependent activation of Tie2 without VE-PTP by Ang1 compared to experimental data by Souma et al.

(C) Simulation of concentration-dependent activation of Tie2 with VE-PTP by Ang2 and concentration-dependent activation of Tie2 without VE-PTP by Ang2 compared to experimental data by Souma et al. Data are presented as mean ± SEM.