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Ang1 Dissociates Tie2 from Tie1:Tie2 Heterodimer
(A) Ang1, but not Ang2, stimulates dissociation of Tie1:Tie2 heterodimer.
(B) The concentration of Tie1:Tie2 heterodimer over time following Ang2 treatment and Ang1 treatment compared to experimental results by Seegar et al.
(C) Heterodimer concentration at 30 min decreases as kdissang1tie1tie2 increases following Ang1 treatment but does not change following Ang2 treatment. Data are presented as mean ± SEM.
See also Figure S3.
