Table 2.
MiR‐27 rs895819 Polymorphism Genotype and Allele Distributions in the Cases and Controls
| Model | Genotype and allele | Cases | Controls | P‐value | OR and 95% CI | Adjusted OR and 95% CIa |
|---|---|---|---|---|---|---|
| Codominant | AA | 245 (48.2%) | 275 (48.9%) | |||
| AG | 176 (34.8%) | 222 (39.5%) | 0.417 | 0.897 (0.690–1.166) | 0.878 (0.671–1.150) | |
| GG | 87 (17.1%) | 65 (11.6%) | 0.027 | 1.508 (1.047–2.171) | 1.546 (1.070–2.236) | |
| Dominant | AA | 245 (48.2%) | 275 (48.9%) | |||
| AG/GG | 263 (51.8%) | 287 (51.1%) | 0.773 | 1.036 (0.815–1.317) | 1.033 (0.809–1.318) | |
| Recessive | GG | 87 (17.1%) | 65 (11.6%) | |||
| AA/AG | 421 (82.8%) | 497 (88.4%) | 0.009 | 0.633 (0.448–0.895) | 0.631 (0.446–0.893) | |
| Overdominant | AG | 176 (34.6%) | 222 (39.5%) | |||
| AA/GG | 332 (65.4%) | 340 (60.5%) | 0.114 | 0.818 (0.638–1.049) | 0.806 (0.624–1.040) | |
| Allele | Allele A | 666 (65.6%) | 772 (68.7%) | |||
| Allele G | 350 (34.4%) | 352 (31.3%) | 0.113 | 1.157 (0.966–1.387) | 1.156 (0.965–1.386) |
a
Adjusted by age, gender, smoking, and drinking.