Table 1.
Personal Characteristics, Activities of Liver Enzymes, Cd4+ Cell Counts, and Activities of Adenosine Deaminases in Healthy Subjects and Infected Patients
| Subjects | N | Gender M/F | Age‐Year Mean (Range) | AST (U/L) Mean (SD) | ALT (U/L) Mean (SD) | ALP (U/L) Mean (SD) | CD4+ count (Cells/μL) Mean (SD) | tADA (U/L) Mean (SD) | ADA1 (U/L) Mean (SD) | ADA2 (U/L) Mean (SD) |
|---|---|---|---|---|---|---|---|---|---|---|
| Control | 72 | 71/1 | 35 (25–60) | 27.2 (4.0)a,b,f | 38.2 (5.4)a,b,c | 85.1 (3.6) | 1748.3 (354.3)a,b,c,d | 23.4 (11.0)a,b,d,e | 6.3 (3.9)a | 16.4 (9.7)a,b,d,e |
| HIV | 33 | 28/5 | 36 (30–55) | 36.0 (2.9)a,c,d | 48.1 (3.6)a,d,e,g | 86.9 (6.1) | 522.8 (275.4)a | 51.5 (12.5)a,c,f,g | 8.1 (5.3) | 43.4 (12.5)a,c,f,g |
| All coinfections | 60 | 57/3 | 34 (23–55) | 34.1 (9.1)f | 43.1 (9.1)g | 85.7 (4.3) | 445.1 (218.5)b | 60.8 (12.2)b,c | 8.2 (5.2) | 52.7 (12.8)b,c |
| HIV‐HBV | 30 | 30/0 | 34 (25–54) | 42.5 (4.2)b,c,e | 51.3 (3.8)b,d,f | 86.7 (9.4) | 387.7 (181.5)c | †59.7 (12.5)d,f | 8.4 (5.4)a | †51.4 (13.2)d,f |
| HIV‐HCV | 30 | 27/3 | 35 (23–55) | 26.4 (4.0)d,e | 35.5 (4.7)c,e,f | 84.8 (4.0) | 517.7 (249.5)d | ‡58.7 (12.7)e,g | 7.7 (4.9) | ‡50.9 (15.3)e,g |
SD, standard deviation; data represented as Mean (SD).
F, female; M, male; U/L, units per liter of enzyme activity.
In each column, data with similar superscript letters (a–g) represents significant difference (P < 0.05) between groups
and ‡represent significant difference of given coinfected group compared with HIV monoinfected subjects with a P value of P = 0.01 and P = 0.02, respectively.