Table 8.
The Predictive Bias and the 95% Confidence Intervals at the Medical Decision Points for two Evaluated Methods
| Evaluated method 1 | Evaluated method 2 | |||
|---|---|---|---|---|
| Ion (mmol/l) | Xrb (mmol/l) | 95% CI of predictive biasa | 95% CI of predictive biasa | Acceptable bias (mmol/l) |
| K | 3.6 | −0.04 (−0.15–0.07) | 0.10 (−0.04–0.24) | ±0.13 |
| 5.2 | −0.03 (−0.14–0.08) | 0.14 (0.01–0.28) | ±0.19 | |
| Na | 136 | 0.43 (0.34–0.53) | 1.11 (0.64–1.57) | ±0.68 |
| 146 | 0.63 (0.54–0.73) | 1.50 (1.03–1.96) | ±0.73 | |
| Cl | 99 | −1.03 (−1.11–0.94) | 0.13 (−0.25–0.51) | ±0.89 |
| 110 | −0.68 (−0.75–0.59) | 0.12 (−0.26–0.49) | ±0.99 |
a
Ninety‐five percent CI of predictive bias was listed in parentheses; the minimal requirements of biological variation for CV (7) were applied as acceptable bias (±3.6% for K, ±0.5% for Na, and ±0.9% for Cl).
b
Xr stands for reference limits.
Applying Olympus indirect ISE method as evaluated method 1, Johnson&Johnson direct ISE method as evaluated method 2, Roche indirect ISE method as the comparative method.