Table 1.
Subject Characteristics of Psoriasis Patients and Controls
| Psoriasis patients (n = 214) | Controls (n = 165) | |||||
|---|---|---|---|---|---|---|
| Mean (SD) | Media (IR) | Mean (SD) | Media (IR) | P‐value | ||
| Age | year | 41.02 (12.55) | 44.00 (20.30) | 42.22 (9.68) | 42.00 (14.00) | 0.116 |
| Gender | M/F (%) | 159/55 (74.30/25.70) | 109/56 (66.06/33.94) | 0.081 | ||
| PASI | – | 15.76 (7.35) | 15.8 (9.00) | – | – | – |
| Peripheral Blood WBC count and classification | ||||||
| WBC | (×109/l) | 6.94 (1.88) | 6.50 (2.31) | 6.17 (1.51) | 6.00 (2.06) | <0.001 |
| Neutrophil granulocyte | (%) | 61.53 (7.94) | 62.20 (10.00) | 58.03 (6.87) | 58.30 (9.60) | 0.002 |
| Neutrophil granulocyte | (×109/l) | 4.30 (1.39) | 4.15 (1.79) | 3.62 (1.17) | 3.53 (1.35) | <0.001 |
| Lymphocyte | (%) | 28.67 (8.83) | 27.40 (11.90) | 32.51 (6.65) | 32.20 (9.10) | 0.003 |
| Lymphocyte | (×109/l) | 1.95 (0.78) | 1.85 (0.87) | 1.98 (0.51) | 2.04 (0.61) | 0.075 |
| Mononuclear leukocyte | (%) | 5.97 (1.95) | 5.45 (2.30) | 6.73 (2.45) | 6.10 (2.20) | <0.001 |
| Mononuclear leukocyte | (×109/l) | 0.41 (0.18) | 0.37 (0.19) | 0.41 (0.15) | 0.39 (0.17) | 0.710 |
| Eosinophilic granulocyte | (%) | 4.07 (3.82) | 3.00 (2.70) | 2.00 (1.01) | 1.80 (0.90) | <0.001 |
| Eosinophilic granulocyte | (×109/l) | 0.31 (0.46) | 0.21 (0.20) | 0.12 (0.06) | 0.10 (0.06) | <0.001 |
| Serum biochemical and immunological index | ||||||
| Alanine aminotransferase | U/l | 23.81 (18.86) | 18.00 (16.00) | 22.51 (14.93) | 17.00 (15.00) | 0.594 |
| Creatine kinase | U/l | 75.95 (46.11) | 64.00 (38.00) | 78.40 (23.95) | 74.50 (30.00) | 0.721 |
| Creatinine | μmol/l | 71.83 (14.71) | 71.00 (23.00) | 68.04 (15.14) | 68.00 (26.00) | 0.095 |
| Total bilirubin | μmol/l | 11.69 (4.47) | 10.95 (5.20) | 13.64 (5.75) | 13.18 (7.80) | <0.001 |
| Immunoglobulin G | g/l | 12.21 (2.53) | 12.00 (3.20) | 11.33 (1.86) | 11.40 (2.40) | 0.002 |
| Immunoglobulin A | g/l | 2.60 (1.35) | 2.33 (1.41) | 2.26 (0.80) | 2.17 (0.99) | 0.064 |
| Immunoglobulin M | g/l | 0.89 (0.34) | 0.83 (0.43) | 1.02 (0.41) | 0.95 (0.54) | 0.001 |
| Complement C3 | g/l | 1.16 (0.24) | 1.13 (0.28) | 1.16 (0.25) | 1.12 (0.37) | 0.890 |
| Complement C4 | g/l | 0.28 (0.20) | 0.26 (0.09) | 0.25 (0.10) | 0.23 (0.07) | 0.020 |
| C‐reactive protein | mg/dl | 9.17 (14.98) | 3.37 (7.02) | 2.66 (2.47) | 2.11 (1.96) | <0.001 |
χ2 test, nonparametric test (Mann–Whitney test), or Student's t‐test were used, the SD is the standard deviation and IR is the interquartile range.