Table 1.
Performances of Three Molecular Assays for Detection of RIF Resistance in Comparison to Culture‐Based Method
| Test method | No. of samples | True positive | False positive | True negative | False negative | Sensitivity (95% CI) | Specificity (95% CI) | P a |
|---|---|---|---|---|---|---|---|---|
| Xpert MTB/RIF | 100 | 47 | 0 | 50 | 3 | 94.0% (83.5–98.8) | 100.0% (92.9–100.0) | NS |
| Sacace MTB Real‐TM resistance | 100 | 45 | 0 | 50 | 5 | 91.8% (80.4–97.7) | 100.0% (92.9–100.0) | NS |
| AdvanSure MDR‐TB GenoBlot | 100 | 42 | 0 | 50 | 8 | 84.0% (70.9–92.8) | 100.00% (92.9–100.0) | 0.0078 |
a
There was no statistical difference between the results for any two molecular assays (P > 0.05, McNemar's test).