Table 2.

Assessment of IHC for HIF‐1 α and PIGF in Control and Preeclamptic Placenta

Protein	Expression	Preeclampsia (N = 45) n (%)	Control (N = 45) n (%)	P values
HIF‐1α nuclear	No staining	0 (0.0)	42(93.3)	0.0001*
	Mild	06 (13.3)	3 (6.6)	0.0001*
	Moderate	10 (22.2)	0 (0.0)	0.0001*
	Intense	29 (64.4)	0 (0.0)	0.0001*
HIF‐1α cytoplasmic	No staining	4(8.9)	0(0.0)	0.0001*
	Mild	41 (91.1)	8 (17.8)	0.0001*
	Moderate	0 (0.0)	18 (40.0)	0.0001*
	Intense	0 (0.0)	19(42.2)	0.0001*
PIGF cytoplasmic	Mild	43(95.6)	0 (0.0)	0.0001*
	Moderate	2 (4.4)	20(44.4)	0.0001*
	Intense	0 (0.0)	25 (55.6)	0.0001*

Pearson chi‐square test (Asymp. sig. [two‐tailed]).

* P < 0.05 is considered significant.

N, no. of cases.