Table 3.
Pathological Background of all Patients With IgAN
| Group L | Group M | Group O | P | |
|---|---|---|---|---|
| Light microscopic findings | ||||
| Total glomeruli (n) | 17.6 ± 7.73 | 16.75 ± 8.36 | 14.24 ± 7.19 | <0.05a |
| Histologic gradec(I:II:III:IV; n) | 48:12:4:1 | 35:17:11:1 | 38:17:9:0 | NSb |
| Number of global sclerosis | 1.6 ± 1.9 | 2.0 ± 2.6 | 1.9 ± 2.4 | NSa |
| Number of segmental sclerosis | 0.4 ± 0.8 | 0.9 ± 2.0 | 0.7 ± 1.3 | NSa |
| Number of crescent | 1.4 ± 2.0 | 1.7 ± 2.6 | 1.0 ± 1.3 | NSa |
| Double contour (n) | 17 | 16 | 12 | NSa |
| Lobulation (n) | 7 | 6 | 2 | NSa |
| Arteriole sclerosis (n) | 15 | 24 | 23 | NSa |
| Tubular atrophy score (0:1:2:3:4:5) | 40:8:0:0:1 | 43:8:0:1:3 | 45:9:0:0:0 | NSb |
| Immunofluorescence findings | ||||
| IgA, n (%) | 32 (37.6) | 25 (29.4) | 28 (32.9) | NSb |
| IgA + IgM, n (%) | 8 (24.2) | 13 (39.4) | 12 (36.4) | NSb |
| IgA + IgG, n (%) | 15 (39.5) | 8 (21.1) | 15 (39.5) | NSb |
| IgA + IgM + IgG, n (%) | 10 (27.0) | 19 (51.4) | 8 (21.6) | <0.05b |
a
Data compared using one‐way factorial ANOVA.
b
Data compared using Fisher's exact test.
c
Japanese classification of IgAN.
NS, not significant.