Table 1.

Protein Bands Identified by LC‐MS/MS

Band		Protein	Gene		Nominal	pI		Peptide	Sequence
no.	Fraction	name	name	AC	mass	value	Score	no.	coverage (%)
Patient A
1	Alb	Serum Alb	ALBU_HUMAN	P02768	71,317	5.92	104	11	26
2	α1	Uromdulin	UROM	P07911	72,451	5.05	24	2	3
3		Alpha‐1‐microglobulin	AMBP_HUMAN	P02760	39,886	5.95	136	4	15
4	α2	Uromodulin	UROM	P07911	72,451	5.05	65	4	5
5		Zinc‐alpha‐2‐glycoprotein	ZA2G_HUMAN	P25311	34,465	5.71	86	6	23
6		Alpha‐1‐microglobulin	AMBP_HUMAN	P02760	39,886	5.95	70	8	19
7	βa	RBP 4	RET4_HUMAN	P02753	23,337	5.76	68	4	30
8	βc	Serotransferrin	TRFE_HUMAN	P02787	79,294	6.81	22	3	7
9		Prostaglandin‐H2 d‐isomerase	PTGDS_HUMAN	P41222	21,243	7.66	88	2	8
10		Ig kappa chain C region	IGKC_HUMAN	P01834	11,773	5.58	31	2	32
11		Lysozyme C	LYZ_HUMAN	P61626	16,982	9.38	79	3	19
11		Cystatin‐C	CYTC_HUMAN	P01034	16,017	9.00	176	3	19
12	ϒ	Ig gamma‐1 chain C region	IGHG1_HUMAN	P01857	36,596	8.46	81	3	50
13		Ig kappa chain C region	IGKC_HUMAN	P01834	11,773	5.58	123	3	48
Patient B
1	X	Transthyretin	TTHY_HUMAN	P02766	15,991	5.52	79	3	17
2	Alb	Serum Alb	ALBU_HUMAN	P02768	71,317	5.92	254	12	48
3	α1	Alpha‐1‐antitrypsin	A1AT_HUMAN	P01009	46,878	5.37	166	4	10
4		Alpha‐1B‐glycoprotein	A1BG_HUMAN	P04217	54,790	5.56	66	9	24
5		Alpha‐1‐microglobulin	AMBP_HUMAN	P02760	39,886	5.95	76	10	21
6	α2	Angiotensinogen	ANGT_HUMAN	P01019	53,406	5.87	100	3	8
7		Vitamin D binding protein	VTDB_HUMAN	P02774	54,526	5.40	77	10	32
8		Apolipoprotein A‐IV	APOA4_HUMAN	P06727	45,371	5.28	21	3	13
9		Zinc‐alpha‐2‐glycoprotein	ZA2G_HUMAN	P25311	34,465	5.71	108	4	10
10		Alpha‐1‐microglobulin	AMBP_HUMAN	P02760	39,886	5.95	130	10	31
11	βa	Plasma protease C1 inhibitor	IC1_HUMAN	Q96FE0	55,347	6.09	89	7	19
12		Complement C1s subcomponent	C1S_HUMAN	Q9UCV3	78,174	4.86	73	9	19
13		Antithrombin‐III	ANT3_HUMAN	Q9UC78	53,025	6.32	60	7	21
14		Spermatogenesis‐associated protein 7	SPAT7_HUMAN	Q9P0W8	68,190	5.90	35	3	7
15		Vitamin D binding protein	VTDB_HUMAN	P02774	54,526	5.40	103	7	28
16		Apolipoprotein A‐IV	APOA4_HUMAN	P06727	45,371	5.28	28	3	21
16		Complement C3 fragment	CO3_HUMAN	P01024	188,569	6.02	67	9	10
17		RBP 4	RET4_HUMAN	P02753	23,337	5.76	81	7	45
18	β	Apolipoprotein A‐IV	APOA4_HUMAN	P06727	45,371	5.28	169	8	21
19		Serotransferrin	TRFE_HUMAN	P02787	79,294	6.81	148	6	10
20		Hemopexin	HEMO_HUMAN	P02790	52,385	6.55	56	5	16
21		β2m	B2MG_HUMAN	P61769	13,715	5.30	34	3	14
22	Y	Pigment epithelium derived factor	PDEF_HUMAN	P36955	46,454	5.97	220	8	20
23		Beta‐2‐glycoprotein 1/Apolipoprotein H	APOH_HUMAN	P02749	39,548	8.34	55	4	17
24		Complement factor H related protein 1	PHR1_HUMAN	Q03591	38766	7.38	37	6	18
25		Apolipoprotein A‐I	APOA1_HUMAN	P02647	30,759	5.56	80	9	32
25		Complement factor D	CFAD_HUMAN	P00746	27,529	7.99	79	7	27
26		Ig kappa chain C region	IGKC_HUMAN	P01834	11,773	5.58	85	3	18
27	ϒ	Ig kappa chain C region	IGKC_HUMAN	P01834	11,773	5.58	97	2	18
28		Beta‐2‐glycoprotein 1/Apolipoprotein H	APOH_HUMAN	P02749	39,548	8.34	63	6	28
29		Beta‐2‐glycoprotein 1/Apolipoprotein H	APOH_HUMAN	P02749	39,548	8.34	337	15	54
29		Apolipoprotein A‐IV	APOA4_HUMAN	P06727	45,371	5.28	62	12	29
30		Immunoglobulin light chain	gi218783334	BAH03697	23,438	8.31	55	5	39
31	Z	Ig gamma‐1 chain C region	IGHG1_HUMAN	P01857	36,596	8.46	63	2	9
31		Ig kappa chain C region	IGKC_HUMAN	P01834	11,773	5.58	116	4	51
31		Ig gamma‐3 chain C region	IGHG3_HUMAN	P01860	42,287	8.23	57	3	9
32		Apolipoprotein A‐IV	APOA4_HUMAN	P06727	45,371	5.28	29	6	18
33		Lysozyme C	LYZ_HUMAN	P61626	16,982	9.38	95	6	37
33		Cystatin‐C	CYTC_HUMAN	P01034	16,017	9.00	62	5	45

The protein band number used in Figure 4c, protein identity, gene name, AC, normal mass, pI value, score, number of peptide matches (peptide no.), and sequence coverage.

AC, accession code.