Figure 3.

Patterns of spine turnover in peri-infarct cortex. A, Examples of spine turnover in peri-infarct cortex over 5 weeks. Scale bar, 10 μm. B, Spine formation was increased in both infarct groups relative to Sham across all postinfarct weeks. C, Spine elimination was increased in both infarct groups relative to Sham at each time point, with the exception of week 4 in RT. Infarct groups did not differ significantly from one another, with the exception of week 5, when spine formation and elimination were significantly lower in the RT versus the No RT group (for details, see text). Data are mean ± SE. *p < 0.02 versus Sham. **p < 0.001 versus Sham. ***p < 0.0001 versus Sham.