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. 2019 Oct 8;30:140–151. doi: 10.1016/j.molmet.2019.09.012

Figure 3.

Figure 3

SCN-BKO mice retain metabolic gene rhythms in peripheral tissues under light-dark, but not under constant darkness conditions. A) mRNA expression profiles of Acat1 (acetyl-CoA acetyltransferase 1) and Glut2 (glucose transporter 2; Slc2a2) in pancreas, Glut2 and Pepck1 (phosphoenolpyruvate carboxykinase) in liver, and Lpin1 (lipin 1), and Atgl (adipose tissue glycerolipase) in eWAT at four time points (Zeitgeber time (ZT) 1 = 1 h after “lights on”) under light-dark conditions in control and SCN-BKO animals. B) mRNA expression profiles of Acat1, Glut2 (pancreas), Glut2, Pepck1 (liver), and Lpin1, Atgl (eWAT) at four time points (circadian time (CT) 1 = 37 h after “lights off”) under constant darkness conditions in control and SCN-BKO animals (n = 3–5 animals per time point and genotype, #: rhythmic gene expression, p < 0.05, CircWave analysis).