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. 2019 Oct 8;30:140–151. doi: 10.1016/j.molmet.2019.09.012

Figure 5.

Figure 5

Impaired glucose utilization in SCN-BKO mice in constant darkness. A) Intraperitoneal glucose (upper panel) and insulin (lower panel) tolerance tests in control (black) and SCN-BKO (red) animals with the corresponding incremental area under the curve (iAUC) evaluation on the right in light-dark (glucose ANOVA: interaction: p = 0.992; time: p < 0.001; genotype: p = 0.530; insulin ANOVA: interaction: p = 0.341; time: p < 0.001; genotype: p = 0.367)) and B) in DD (glucose ANOVA: interaction: p = 0.090; time: p < 0.001; genotype: p = 0.111; insulin ANOVA: interaction: p = 0.741; time: p < 0.001; genotype: p = 0.112) (n = 6 animals per genotype; iAUC: *: p < 0.05, unpaired Student's t-test).