Table 2.

Allele, Genotype, and Haplotype Frequency Distributions of IL‐10 Genetic Polymorphisms in the Taiwanese KD Patients With CAAs and Controls

Gene name (nucleotide change; SNP database ID)	Genotype	Ctrl	KD With CAAs	P	OR	95% CI
IL‐10 ‐1082 (A/G)
(rs1800896)	GG	0 (0.0%)	0 (0.0%)	0.015*
	AG	14 (5.1%)	8 (13.8%)		3.01	1.2–7.54
	AA	263 (94.9%)	50 (0.862)		1.00
	G allele	14 (2.5%)	8 (6.9%)	0.016*	2.86	1.17–6.98
	A allele	540 (97.5%)	108 (93.1%)		1.00
IL‐10 ‐819 (C/T)
(rs1800871)	TT	115 (41.4%)	28 (48.3%)	0.112	0.68	0.28–1.61
	CT	138 (49.6%)	21 (36.2%)		0.42	0.17–1.03
	CC	25 (9.0%)	9 (15.5%)		1.00
	T allele	368 (66.2%)	77 (66.4%)	0.968	1.01	0.66–1.54
	C allele	188 (33.8%)	39 (33.6%)		1.00
IL‐10 ‐592 (C/A)
(rs1800872)	CC	23 (8.3%)	9 (16.0%)	0.110	1.68	0.70–4.02
	AC	134 (48.4%)	21 (36.2%)		0.67	0.36–1.24
	AA	120 (43.3%)	28 (48.3%)		1.00
	C allele	180 (32.5%)	39 (33.6%)	0.814	1.05	0.69–1.61
	A allele	374 (67.5%)	77 (66.4%)		1.00
Haplotype (‐1082/‐819/‐592)
	ATA	186 (67.3%)	39 (66.4%)	0.843
	ACC	84 (30.2%)	15 (26.7%)	0.463
	GCC	7 (2.5%)	4 (6.9%)	0.016*

CI, confidence interval; Ctrl, control subject; OR, odds ratio.

Numbers in parentheses indicate allele or genotype frequency percentages.

Numbers in bold italics indicate statistically significant differences.

Allele and genotype frequency distributions in the polymorphism at the IL‐10 (‐1082) position (rsl 800896) in the KD patients and controls were analyzed using the chi‐square test method (2 × 2 tables).

The P values were adjusted by using Bonferroni's correction. Statistical significance was considered as P‐value < 0.017 (0.05/3).