Table 1.
Comparison of the Serum Fibrosis Direct Indices and the FibroTest Index in the Patient and Control Groups
| Patient group | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Inflammation grade (n = 108) | Fibrosis stage (n = 108) | Control group | |||||||||
| Index | n = 108 Mean | G1 (n=16) | G2 (n=21) | G3 (n=51) | G4 (n=20) | S0 (n=12) | S1 (n=18) | S2 (n=21) | S3 (n=20) | S4 (n=37) | n = 53 Mean |
| HA (ng/ml) | 63.95a | 40.55 | 35.77 | 76.63 | 104.68c | 56.49 | 47.30 | 47.99 | 66.31 | 88.78 | 34.72b |
| CIV (ng/ml) | 67.32a | 40.66 | 35.49 | 74.25 | 144.35c | 49.27 | 28.46 | 53.32 | 86.86 | 112.74 | 23.31b |
| LN (ng/ml) | 78.39a | 32.03 | 22.72 | 120.38 | 174.20c | 30.89 | 21.22 | 75.86 | 130.27 | 154.84 | 30.67b |
| PIIINP (ng/ml) | 9.26a | 5.95 | 6.13 | 10.01 | 15.95c | 9.77 | 4.88 | 9.86 | 8.73 | 12.36 | 3.90b |
| FibroTest index | 0.41 | −0.24 | −0.27 | 0.34 | 1.74 | −0.90 | −0.24 | 0.23 | 0.62 | 1.15 | −0.84 |
| ±1.55a | ±1.84 | ±1.26 | ±1.20 | ±1.53c | ±1.06 | ±1.39 | ±1.28 | ±1.29 | ±1.63c | ±1.15b | |
a
Comparison between the patient and control groups, P < 0.05.
b
In comparison to the G3, G4/S3, and S4 patients, P < 0.001.
c
The indices of the G4 patients were significantly higher than those of the G1 and G2 patients, and the FibroTest index of the S4 patients was significantly higher than those of the S1 and S2 patients, P < 0.01.
In the table, the HA, CIV, LN, and PIIINP values represent the geometric mean values, whereas the value of FibroTest index is the arithmetic mean ± standard deviation.