Table 4.
The Diagnostic Ability of Five Indices to Detect Liver Fibrosis (≥S1)
AUC | 95% CI of AUC | Sensitivity (%) | Specificity (%) | Youden index | Positive predictive value (%) | Negative predictive value (%) | Positive likelihood ratio | Negative likelihood ratio | |
---|---|---|---|---|---|---|---|---|---|
HA | 0.626 | 0.539‐0.713 | 83.33 | 38.46 | 0.22 | 66.70 | 61.00 | 1.35 | 0.43 |
CIV | 0.771 | 0.696‐0.845 | 76.04 | 73.85 | 0.50 | 81.10 | 67.60 | 2.91 | 0.32 |
LN | 0.738 | 0.663‐0.814 | 52.08 | 95.38 | 0.47 | 94.30 | 57.40 | 11.27 | 0.50 |
PIIINP | 0.735 | 0.678‐0.831 | 67.71 | 76.92 | 0.45 | 81.30 | 61.70 | 2.93 | 0.42 |
FibroTest | 0.80 | 0.729‐0.871 | 68.75 | 83.08 | 0.52 | 85.70 | 64.30 | 4.06 | 0.38 |
Four indices combined | ‐ | ‐ | 93.75 | 30.77 | 0.25 | 66.67 | 76.92 | 1.35 | 0.20 |
Five indices combined | ‐ | ‐ | 99.00 | 29.20 | 0.28 | 67.40 | 95.00 | 1.40 | 0.03 |