Table 2.
Within‐run and Between‐run Imprecision of Dimension Vista® Methods
| Analyte | Within run (n = 20) | Between‐run (n = 29) | ||||||
|---|---|---|---|---|---|---|---|---|
| PLASMA | m | CV% | m | CV% | m | CV% | m | CV% |
| Sodium (mmol/l) | 135.85 | 0.27 | 148.25 | 0.30 | 127.15 | 1.63 | 142.50 | 1.03 |
| Potassium (mmol/l) | 4.83 | 0.19 | 5.68 | 0.24 | 4.80 | 1.72 | 5.41 | 0.41 |
| Chloride (mmol/l) | 95.10 | 0.90 | 105.05 | 0.21 | 103.30 | 1.69 | 108.15 | 4.34 |
| Total CO2 (mmol/l) | 17.91 | 1.37 | 28.08 | 1.44 | 17.12 | 12.30 | 26.20 | 7.28 |
| Total Proteins (g/l) | 43.10 | 0.71 | 71.95 | 0.55 | 46.25 | 2.79 | 70.18 | 1.34 |
| Urea (mmol/l) | 6.18 | 1.67 | 17.30 | 2.25 | 6.31 | 1.86 | 17.48 | 2.07 |
| Creatinine (μmol/l) | 102.74 | 3.84 | 634.24 | 0.76 | 112.50 | 7.16 | 686.44 | 1.28 |
| Glucose (mmol/l) | 5.23 | 1.12 | 14.56 | 1.17 | 6.16 | 1.13 | 17.12 | 1.16 |
| Triglycerides (mmol/l) | 1.20 | 2.57 | 2.15 | 1.06 | 2.34 | 2.92 | nd | nd |
| Cholesterol (mmol/l) | 10.59 | 1.15 | 21.82 | 1.49 | 2.77 | 2.36 | 5.39 | 1.47 |
| Calcium (mmol/l) | 2.53 | 0.89 | 2.90 | 1.18 | 2.45 | 1.46 | 2.80 | 1.21 |
| Phosphorus (mmol/l) | 1.59 | 0.94 | 2.37 | 1.40 | 1.66 | 2.15 | 2.24 | 3.59 |
| Uric Acid (μmol/l) | 300 | 0.95 | 607 | 0.98 | 316.09 | 2.31 | 678.71 | 2.14 |
| Lactic Acid (mmol/l) | 2.35 | 2.18 | 5.73 | 1.51 | nd | nd | nd | nd |
| Total Bilirubin (μmol/l) | 15.54 | 1.87 | 60.98 | 0.89 | 119.36 | 1.76 | 335.43 | 2.69 |
| Direct Bilirubin (μmol/l) | 6.72 | 4.56 | 26.11 | 2.05 | 104.68 | 2.36 | nd | nd |
| AST (IU/l) | 28.70 | 3.77 | 188.00 | 0.91 | 32.69 | 7.77 | 194.00 | 1.14 |
| ALT (IU/l) | 43.90 | 2.33 | 106.35 | 2.54 | 36.53 | 5.80 | 77.67 | 2.82 |
| ALP (IU/l) | 102.95 | 2.39 | 404.95 | 1.71 | 146.33 | 4.08 | 430.32 | 3.57 |
| GGT (IU/l) | 57.60 | 2.21 | 152.10 | 0.70 | 59.00 | 3.36 | 144.73 | 1.79 |
| CK (IU/l) | 165.80 | 1.20 | 402.95 | 1.05 | 162.79 | 2.43 | 377.61 | 2.94 |
| LDH (IU/l) | 175.60 | 1.76 | 402.85 | 1.61 | 168.11 | 2.82 | 378.79 | 4.19 |
| Amylase (IU/l) | 104.85 | 0.64 | 320.95 | 0.81 | 114.45 | 1.59 | 347.10 | 2.04 |
| Lipase (IU/l) | 134.75 | 2.39 | 406.25 | 1.89 | 198.35 | 4.97 | 313.20 | 5.07 |
| cTnI (ng/ml) | 0.256 | 2.68 | 1.338 | 0.94 | 0.134 | 4.11 | 3.20 | 2.96 |
| βHCG (IU/l) | 7.40 | 2.06 | 22.19 | 1.04 | nd | nd | nd | nd |
| Nt‐proBNP (pg/ml) | 173.44 | 0.97 | 805.74 | 1.36 | nd | nd | 1,964 | 4.44 |
| Albumin (g/l) | 29.82 | 1.99 | 48.57 | 1.41 | 26.01 | 3.02 | 44.51 | 2.13 |
| α1‐acid glycoprotein (g/l) | 0.83 | 2.21 | 1.25 | 1.56 | 0.54 | 4.20 | 0.74 | 4.21 |
| α1‐antitrypsin (g/l) | 0.98 | 3.47 | 2.34 | 3.49 | 0.98 | 3.26 | 1.31 | 3.92 |
| Haptoglobin (g/l) | 0.81 | 2.30 | 1.19 | 1.58 | 0.75 | 4.05 | 0.98 | 3.69 |
| CRP (mg/l) | 12.05 | 3.57 | 47.76 | 1.47 | 12.46 | 5.23 | 52.11 | 3.52 |
| hsCRP(mg/l) | 1.21 | 1.83 | 3.90 | 1.31 | 1.45 | 4.12 | 4.50 | 2.41 |
| Ferritin (ng/ml) | 55.89 | 1.43 | 239.80 | 1.44 | 55.41 | 1.74 | 375.74 | 4.02 |
| Transferrin (g/l) | 2.55 | 2.01 | 3.17 | 2.13 | 2.07 | 1.58 | 3.56 | 2.20 |
| URINE | m | CV% | m | CV% | m | CV% | m | CV% |
|---|---|---|---|---|---|---|---|---|
| Sodium (mmol/l) | 75.90 | 0.84 | 146.05 | 0.61 | 86.20 | 3.84 | 165.63 | 1.86 |
| Potassium (mmol/l) | 28.96 | 0.63 | 82.85 | 0.72 | 28.45 | 0.72 | 80.26 | 0.50 |
| Chloride (mmol/l) | 56.45 | 0.90 | 159.90 | 0.35 | 61.13 | 3.01 | 179.35 | 0.55 |
| Urea (mmol/l) | 139.71 | 1.87 | 309.65 | 1.53 | 146.58 | 2.45 | 260.02 | 2.11 |
| Creatinine (mmol/l) | 5.61 | 0.92 | 13.41 | 0.68 | 6.59 | 3.42 | 13.02 | 3.28 |
| Glucose (mmol/l) | 1.19 | 1.47 | 15.12 | 0.79 | 1.32 | 1.42 | 16.35 | 0.87 |
| Proteins (g/l) | 1.42 | 6.00 | 7.01 | 1.50 | nd | nd | 6.69 | 1.99 |
| Microalbuminuria (mg/l) | nd | nd | nd | nd | nd | nd | nd | nd |
Bold: CV exceeds the acceptable limit according to VALTEC; nd, not done.
Appropriate criteria for the evaluation of the imprecision were published by Vassault et al. in 1999 4.