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. 2013 Nov 11;27(6):494–503. doi: 10.1002/jcla.21633

Table 3.

Comparisons of Biomarkers in the Subjects With Different MnSOD1183T>C Genotypes

MnSOD1183T>C
Heavy drinkersa Nonheavy drinkersb
TT TC + CC TT TC + CC
Parameters (n = 88) (n = 20) (n = 73) (n = 33)
Hematological test
MCV (fl) 90.5 ± 7.6 90.1 ± 5.5 87.4 ± 7.3 87.5 ± 8.4
Biochemical tests
AST (U/l) 28 ± 19 25 ± 7 23 ± 8 21 ± 6
ALT (U/l) 33 ± 19 32 ± 16 31 ± 20 29 ± 14
AST/ALT 0.9 ± 0.3 0.9 ± 0.3 0.8 ± 0.2 0.8 ± 0.2
GGT (U/l) 52 ± 36 54 ± 33 28 ± 13 27 ± 18
CDT (%) 1.7 ± 0.6 1.9 ± 1.0 1.4 ± 0.3 1.4 ± 0.5
MDA (μmol/l) 1.8 ± 1.5 1.6 ± 1.4 1.5 ± 1.0 1.4 ± 0.9
Immunological tests
CD3+ cells (%) 65.8 ± 9.6 66.3 ± 8.5 62.8 ± 7.8 65.7 ± 9.8
CD4+ cells (%) 36.5 ± 9.3 34.3 ± 8.3 32.6 ± 7.9 30.4 ± 8.5
CD8+ cells (%) 22.7 ± 6.8 21.2 ± 5.2 23.4 ± 5.7 26.5 ± 7.8*
CD19+ cells (%) 10.8 ± 4.2 13.2 ± 4.5* 12.4 ± 4.5 11.1 ± 4.5
IgG (mg/dl) 1126 ± 227 1132 ± 274 1209 ± 272 1233 ± 202
IgM (mg/dl) 90 ± 45 88 ± 39 100 ± 42 132 ± 71
IL‐2R (U/l) 365 ± 129 412 ± 166 372 ± 157 341 ± 114
IL‐6 (ng/ml) 3.9 ± 2.1 4.6 ± 1.9 3.5 ± 2.1 2.9 ± 1.5
IL‐8 (ng/ml) 10.4 ± 4.9 10.3 ± 5.2 9.8 ± 6.6 7.9 ± 3.5
IL‐10 (ng/ml) 1.9 ± 1.1 2.1 ± 0.8 1.9 ± 1.3 1.5 ± 1.0
TNF‐α (pg/ml) 10.2 ± 8.4 7.5 ± 2.3* 10.6 ± 9.0 10.1 ± 9.0

a*P <0.05 compared with the subjects with the TT genotypes in the heavy drinkers.

b*P <0.05 compared with the subjects with the TT genotypes in the nonheavy drinkers.

MCV, mean corpuscular volume; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma‐glutamyl transferase; carbohydrate‐deficient transferring; MDA, malondialdehyde; CD, cluster differentiation; Ig, immunoglobulin; IL, interleukin; TNF, tumor necrosis factor.