Table 5.

Comparisons of the Biomarkers in the Subjects With Different Combined Genotypes of MnSOD1183T>C and PX1Pro198Leu

	Heavy drinkers				Nonheavy drinkers
	MnSOD TT		MnSOD TC + CC		MnSOD TT		MnSOD TC + CC
	GPX1	GPX1	GPX1	GPX1	GPX1	GPX1	GPX1	GPX1
	CC [A]	CT [B]	CC [C]	CT [D]	CC [A]	CT [B]	CC [C]	CT [D]
Parameters	(n = 81)	(n = 7)	(n = 15)	(n = 5)	(n = 66)	(n = 8)	(n = 25)	(n = 7)
Immunological tests
CD3+ cells (%)	65.6 ± 9.7	68.5 ± 7.4	65.4 ± 9.6	69.0 ± 1.8	62.5 ± 7.7	65.5 ± 8.0	66.4 ± 8.6	63.4 ± 15.0
CD4+ cells (%)	36.2 ± 9.4	39.7 ± 7.7	32.6 ± 7.9	39.3 ± 8.2	32.5 ± 7.9	32.8 ± 7.6	30.6 ± 8.1	30.0 ± 11.0
CD8+ cells (%)	22.8 ± 7.0	22.1 ± 4.5	21.1 ± 5.1	21.4 ± 6.3	23.2 ± 5.6	23.5 ± 5.4	27.3 ± 8.1	26.0 ± 7.7
CD19+ cells (%)	10.8 ± 4.2	10.9 ± 4.2	12.1 ± 4.1	16.8 ± 4.2a	12.3 ± 4.7	12.1 ± 2.3	11.7 ± 4.8	9.8 ± 3.3
IgG (mg/dl)	1131 ± 216	1020 ± 343	1089 ± 228	1262 ± 381	1234 ± 274	1019 ± 106	1240 ± 209	1194 ± 223
IgM (mg/dl)	89 ± 44	106 ± 53	79 ± 30	116 ± 53	97 ± 41	118 ± 54	134 ± 57a	142 ± 105
IL‐2R (U/l)	365 ± 131	361 ± 115	383 ± 159	500 ± 172	380 ± 161	337 ± 131	334 ± 112	332 ± 108
IL‐6 (ng/ml)	3.9 ± 2.1	3.5 ± 1.8	4.4 ± 1.9	5.3 ± 2.1	3.4 ± 2.0	4.2 ± 2.8	2.7 ± 1.2	3.0 ± 2.0
IL‐8 (ng/ml)	10.5 ± 5.0	9.7 ± 3.8	10.3 ± 5.9	10.2 ± 2.8	9.4 ± 5.3	9.6 ± 9.4	7.6 ± 3.1	12.5 ± 11.2
IL‐10 (ng/ml)	1.9 ± 1.1	1.9 ± 0.7	2.0 ± 0.7	2.1 ± 1.3	1.9 ± 1.3	1.7 ± 1.1	1.6 ± 1.0	1.4 ± 1.1
TNF‐α (pg/ml)	10.4 ± 8.7	7.9 ± 2.6	6.9 ± 2.1	9.3 ± 2.0	10.4 ± 9.2	10.3 ± 5.8	8.4 ± 4.4	18.1 ± 16.8

The alphabet in the square bracket indicates the group of the study.

^a P <0.05, compared with Group A in the heavy drinkers or nonheavy drinkers, respectively.

CD, cluster differentiation; Ig, immunoglobulin; IL, interleukin; TNF, tumor necrosis factor.