Table 1.
The Relation Between the Variables Measured and CAD Severity Score
| CAD severity score | ||||||
|---|---|---|---|---|---|---|
| 0 | 1–20 | 20–50 | 50 | P (ANCOVA) | ||
| Number of patients | 91 | 93 | 65 | 56 | ||
| Gender | 68H/23F | 73H/20F | 49H/16F | 42H/14F | ||
| Age | (years, X ± δ) | 59.8 ± 9.9 | 60.2 ± 11.8 | 61.1 ± 10.1 | 60.5 ± 13.9 | <0.01 |
| BMI | (Kg/m2, X ± δ) | 28.3 ± 5.1 | 27.6 ± 5.2 | 26.3 ± 3.6 | 24.8 ± 5.5 | 0.001 |
| TC | (mmol/l, X ± δ) | 4.0 ± 0.9 | 4.3 ± 1.4 | 4.3 ± 0.8 | 4.4 ± 0.8 | <0.01 |
| HDLc | (mmol/l, X ± δ) | 1.08 ± 0.3 | 1.07 ± 0.4 | 1.07 ± 0.2 | 1.05 ± 0.3 | <0.01 |
| TG | (mmol/l, X ± δ) | 1.8 ± 1.3 | 1.8 ± 0.9 | 1.8 ± 1.1 | 2.2 ± 0.6 | 0.03 |
| Apo (A1) | (g/l, X ± δ) | 1.5 ± 1.2 | 0.9 ± 0.6 | 0.9 ± 0.5 | 0.89 ± 2.2 | 0.001 |
| Apo (B) | (g/l, X ± δ) | 1.3 ± 0.4 | 1.4 ± 0.4 | 1.5 ± 0.6 | 1.7 ± 0.5 | 0.01 |
| Cystatin C | (mg/l, X ± δ) | 0.7 ± 0.2 | 0.8 ± 0.3 | 1.2 ± 0.9 | 2.9 ± 2.2 | <0.01 |
| Creatinine | (μmol/l, X ± δ) | 71.1 ± 8 | 73.3 ± 8.01 | 83.2 ± 8.2 | 125.6 ± 6.2 | <0.01 |
| eGFR | (ml/min/1.73 m2, X ± δ) | 96.1 ± 3.5 | 94.3 ± 3.2 | 88.3 ± 4.01 | 73.2 ± 5.5 | 0.04 |
| Log hs‐CRP | 0.62 ± 0.5 | 0.68 ± 0.58 | 0.69 ± 0.46 | 0.7 ± 0.56 | 0.01 | |
| Fibrinogen | (g/l, X ± δ) | 3.9 ± 1.4 | 3.6 ± 1.1 | 4.2 ± 1.4 | 5.5 ± 1.7 | 0.01 |
| GPX | (U/gHb, X ± δ) | 62.1 ± 10.4 | 59 ± 10.5 | 56.6 ± 9.6 | 57 ± 10 | <0.001 |
| GR | (U/gHb, X ± δ) | 2.6 ± 0.8 | 2.4 ± 0.8 | 2.29 ± 0.7 | 2.1 ± 0.4 | 0.001 |
| CAT | (μmol H2O2/min/mg proteins) | 1 ± 0.08 | 1.06 ± 0.04 | 1.02 ± 0.1 | 1 ± 0.05 | <0.001 |
| SOD | (U/gHb, X ± δ) | 687.9 ± 454.7 | 662.3 ± 351.4 | 553.7 ± 361.3 | 558.8 ± 464.4 | <0.001 |
| TAS | (mmol/l, X ± δ) | 1.1 ± 0.3 | 1.1 ± 0.2 | 1.10 ± 0.3 | 1.3 ± 0.2 | <0.001 |
| Lipid peroxides as malondialdehyde | (μmol/l, X ± δ) | 1.8 ± 0.3 | 1.8 ± 0.3 | 1.9 ± 0.2 | 1.95 ± 0.2 | <0.001 |
| homocyteine | (μmol/l, X ± δ) | 9.8 ± 5.5 | 12.21 ± 6.1 | 13.36 ± 4.3 | 15.91 ± 6.8 | <0.001 |
Data are expressed as mean ± SD or number.
BMI: body mass index; H: men; F: women; TC: total cholesterol; HDLc: high‐density lipoprotein cholesterol; TG: triglycerides; Apo (A1) and Apo (B): apolipoproteins; eGFR: estimated glomerular filtration rate; hs‐CRP: high‐sensitive C‐reactive protein; TAS: total antioxidant status; GPX: glutathione peroxidase; GR: glutathione reductase; CAT: catalase; SOD: superoxide dismutase.
P‐value is from χ2 test.