TABLE 2.
List of brain ROIs that were significantly different within at least one of the experimental factors (i.e., condition or time) in nodal properties over more than half of the adjacency matrices (with δ values from 0.06 to 0.3 in a step of 0.01).
| ROI (modules) |
MNI coordinates |
AAL label |
p-value (δ) |
||||||||
| x | y | z | Degree | Betweenness | Participation | K-coreness | Sub-graph | Eigenvector | PageRank | ||
| 9 (FPN) | −31 | 50 | −10 | Frontal_Mid_Orb_L | 0.0154 (0.06)t | 0.004 (0.09)t | |||||
| 20 (SMN) | 9 | 0 | 62 | Supp_Motor_Area_R | 0.0063 (0.19)t | 0.0287 (0.21)c | 0.004 (0.23)t | 0.0273 (0.19)t | |||
| 24 (DMN) | 9 | 51 | 30 | Frontal_Sup_Medial_R | 0.0018 (0.08)t | 0.021 (0.25)t | 0.0038 (0.06)t | 0.0018 (0.07)t | 0.024 (0.06)t | ||
| 25 (DMN) | −5 | 54 | −7 | Frontal_Med_Orb_L | 0.00007 (0.1)t | 0.00001 (0.06)t | 0.00006 (0.28)t | 0.00003 (0.28)t | |||
| 26 (DMN) | 8 | 52 | −7 | Frontal_Med_Orb_R | 0.0008 (0.12)t | 0.0103 (0.06)t | 0.00037 (0.18)t | 0.0181 (0.28)t | |||
| 27 (DMN) | −5 | 37 | −18 | Rectus_L | 0.0044 (0.09)t | ||||||
| 28 (DMN) | 8 | 36 | −18 | Rectus_R | 0.0161 (0.17)t | 0.0007 (0.12)t | 0.0128 (0.17)t | 0.0208 (0.2)t | |||
| 34 (LS) | 8 | −9 | 40 | Cingulum_Mid_R | 0.0005 (0.11)c | ||||||
| 37 (LS) | −25 | −21 | −10 | Hippocampus_L | 0.0013 (0.17)t | ||||||
| 38 (LS) | 29 | −20 | −10 | Hippocampus_R | 0.0073 (0.15)c | ||||||
| 39 (LS) | −21 | −16 | −21 | ParaHippocampal_L | 0.0005 (0.07)t | 0.0002 (0.07)t | 0.00006 (0.07)t | 0.00006 (0.15)t | |||
| 40 (LS) | 25 | −15 | −20 | ParaHippocampal_R | 0.0264 (0.13)t | ||||||
| 41 (LS) | −23 | −1 | −17 | Amygdala_L | 0.0244 (0.3)t | 0.0055 (0.17)t | 0.0162 (0.23)t | 0.0127 (0.3)t | |||
| 42 (LS) | 27 | 1 | −18 | Amygdala_R | 0.0391 (0.26)c | ||||||
| 46 (VN) | 14 | −79 | 28 | Cuneus_R | 0.0235 (0.06)c 0.0048 (0.12)t |
0.017 (0.25)c | 0.0022 (0.08)t | 0.0221 (0.1)c 0.0045 (0.17)t | 0.0189 (0.22)c 0.0101 (0.12)t | ||
| 50 (VN) | 24 | −81 | 31 | Occipital_Sup_R | 0.0007 (0.11)t | 0.0004 (0.11)t | 0.0002 (0.17)t | 0.004 (0.19)t | |||
| 52 (VN) | 37 | −80 | 19 | Occipital_Mid_R | 0.0149 (0.17)t | 0.0103 (0.06)t | 0.0206 (0.07)t | ||||
| 54 (VN) | 38 | −82 | −8 | Occipital_Inf_R | 0.0023 (0.11)c | ||||||
| 56 (VN) | 34 | −39 | −20 | Fusiform_R | 0.0271 (0.22)c | 0.0169 (0.13)t | |||||
| 59 (SMN) | −23 | −60 | 59 | Parietal_Sup_L | 0.0008 (0.14)t | ||||||
| 61 (FPN) | −43 | −46 | 47 | Parietal_Inf_L | 0.0066 (0.16)t | 0.0141 (0.15)t | 0.022 (0.19)t | 0.0082 (0.19)t | |||
| 73 (LS) | −24 | 4 | 2 | Putamen_L | 0.0231 (0.3)c | ||||||
| 74 (LS) | 28 | 5 | 2 | Putamen_R | 0.0059 (0.16)t | 0.0118 (0.07)t | 0.0093 (0.14)t | 0.0048 (0.07)t | |||
| 75 (LS) | −18 | 0 | 0 | Pallidum_L | 0.02 (0.3)c | 0.0108 (0.13)c | 0.0199 (0.3)c | 0.0355 (0.15)c | |||
| 85 (DMN) | −56 | −34 | −2 | Temporal_Mid_L | 0.0395 (0.21)c | ||||||
| 86 (DMN) | 57 | −37 | −1 | Temporal_Mid_R | 0.0024 (0.15)t | ||||||
| 100 (CERB) | 26 | −58 | −24 | Cerebelum_6_R | 0.0049 (0.13)t | 0.0048 (0.14)t | 0.0076 (0.13)t | ||||
| 108 (CERB) | 27 | −34 | −41 | Cerebelum_10_R | 0.025 (0.18)t | 0.0015 (0.19)c | 0.0322 (0.23)c | 0.0132 (0.12)t | |||
The minimum FDR adjusted p-value at its corresponding threshold is specified for each local feature. The superscripts c and t represent the condition and time factor, respectively. MNI, Montreal Neurological Institute space; AAL, Automated Anatomical Labeling atlas; SMN, sensorimotor network; VN, visual network; FPN, frontoparietal network; DMN, default mode network; LS, limbic system; CERB, cerebellar network.